Heart White
Why do black men use different heart medication to white men?
On an episode of House a black man was given different heart medication to what a white man would receive. Apparently this medication was specially designed to work better for black men. I’m curious as to what difference exists between white and black men that they might use two different medications?
Well the show was quite specific that this was a racial issue deciding what medication the man should take. Of course the show is hardly a scholarly reference but it intrigued me none the less.
So different races are genetically different to each other in any way other than the genetic differences that define us as indivduals? What about skin pigment? Obviously that’s different between races, is that not related to genetics?
Doctors would like to know, too. I didn’t see the show, so I don’t know which medication you’re talking about, but there are several significant differences in how blacks and whites respond to cardiovascular medications. That holds for men and women, as well. But the drugs aren’t designed that way. For instance, the use of hydralazine in afterload reduction for congestive heart failure seems to work very well in blacks, according to recent studies, but the drug’s been used for decades. Perhaps even more interesting is that CMS looks at the prescription of certain drugs as markers of quality, and this isn’t one of them, despite the fact that it’s cheaper and works better than the alternative in selected patients.
In drug treatment studies, one of the important things to do is to check for “confounding variables” that might skew the results. Sometimes something unexpected like a racial difference pops up. That in itself is meaningless, but it does offer the hypothesis for later study, and that’s the stage at which we find ourselves with some of these drugs. Stay tuned.
White Heart – Desert Rose
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